Signal Transduction Reagents and Kits
Promega GSH-Glo™ Glutathione Assay
The GSH-Glo™ Assay is a luminescent-based assay for the detection and quantification of glutathione (GSH) in cells or in various biological samples.
Promega NADPH Regeneration System
The NADPH Regeneration System is an enzyme substrate combination that reduces NADP+ to NADPH.
Promega P450-Glo™ CYP1A2 Induction/Inhibition Assay
The P450-Glo™ CYP1A2 Assay and Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays
Promega P450-Glo™ CYP3A4 Assay (Luciferin-PPXE) DMSO-Tolerant Assay
The P450-Glo CYP3A4 Assay System provides a homogeneous, luminescent method for measuring CYP3A4 activity and the screening system contains a complete set of reagents for performing the assay.
Promega ADP-Glo™ Kinase Assay+ MAPKAPK2 Kinase Enzyme System
Recombinant human MAPKAPK2 (46-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. MAPKAPK2 (MAPKAP kinase2) is a Ser/Thr protein kinase that is regulated via direct phosphorylation by p38 MAP kinase.
Promega cAMP-Glo™ Assay
The cAMP-Glo™ Assay is a homogeneous, bioluminescent and high-throughput assay for measuring cAMP levels in cells
Promega ONE-Glo™ Assay
The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health. The assay uses a two-step, addition-only process to measure in a single well of a plate.
Promega Luciferin Detection Reagent with Esterase
A reagent to detect presence of pro-luciferin substrates used to monitor the activity of specific isoforms of cytochrome P450 or NAT2.
Promega ADP-Glo™ Kinase Assay + JNK3 Kinase Enzyme System
Recombinant full-length human JNK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. JNK3 is a member of the c-Jun N-terminal kinases (JNKs), which are part of the mitogen-activated protein (MAP) kinase family.
Promega ADP-Glo™ Kinase Assay + PAK4 Kinase Enzyme System
Recombinant full-length human PAK4 was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. PAK4 is a member of the p21-activated kinases (PAKs), which have been implicated in the regulation of cell morphology, motility and transformation.
Promega P450-Glo CYP3A4 Screening System (Luciferin-PPXE) DMSO-Tolerant Assay
The P450-Glo™ CYP3A4 Assay System provides a homogeneous, luminescent method for measuring CYP3A4 activity and the screening system contains a complete set of reagents for performing the assay.
Promega ADP-Glo Kinase Assay + ASK1 Kinase Enzyme System, 1 each
Recombinant human ASK1 (649-946) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. ASK1, also known as MAPKKK5, activates MKK3, MKK4 (SEK1) and MKK6. Overexpression of ASK1 induces apoptotic cell death.
Promega Caspase-Glo 1 Inflammasome Assay, 5 x 10ml
The Caspase-Glo 1 Inflammasome Assay is a homogeneous, bioluminescent method to selectively measure the activity of caspase-1, a member of the cysteine aspartic acid-specific protease (caspase) family and an essential component of the inflammasome.
Promega Glutamate-Glo Assay, 5ml
The Glutamate-Glo Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamate in biological samples. The assay couples glutamate oxidation and NADH production with a bioluminescent NADH detection system.
Promega PKC zeta Kinase Enzyme System, 1mg
Recombinant full-length human PKC zeta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC zeta is an atypical isoform of the PKC family.